http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022104385-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3155069b833b184bcd4ad12f7100dd4c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 |
filingDate | 2021-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b0775c50457bd37b3a666c6ff952617 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_788148286c1ed4e3676acb61d50ce0f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edfd063efe9539a43c85e70b080f4783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14c90866d429a7b5d02188fcc97452fd |
publicationDate | 2022-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2022104385-A2 |
titleOfInvention | Stability and activity of enzymes by immobilization |
abstract | A polymer brush composed of statistical copolymers of hydrophilic and hydrophobic monomers for enzyme immobilization. The heterogeneous polymer brushes stabilized four different lipases against high temperatures. Notably, the statistical copolymers stabilized the four lipases to a greater extent than a homopolymer brush. Additionally, in the case of Rhizomucor miehei lipase, statistical copolymers stabilized the enzyme to a greater extent than homopolymers of either hydrophilic or hydrophobic monomers. The resulting increase in high-temperature stability enabled significant improvements in catalytic rates by operating reactions at elevated temperatures, which is desirable for enzyme catalysis and sensing applications. Additionally, stabilization against elevated temperatures implies stabilization against non-aqueous solvents, which is of critical importance to numerous applications of biocatalysts. |
priorityDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.