| abstract |
This document provides methods and materials for identifying and/or treating a mammal (e.g., a human) having, or at risk of developing, heart failure (e.g., inherited heart failure). For example, methods and materials for identifying a mammal (e.g., a human) having, or at risk of developing, heart failure (e.g., inherited heart failure) by detecting the presence of a mutation in both copies of a KCNJ11 gene present in the mammal (e.g., a human) are provided. Methods and materials for treating a mammal (e.g., a human) identified as having, or as being at risk of developing, heart failure (e.g., inherited heart failure) also are provided. |