http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022098768-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a7ebd2ce5ef7e691bd44c48a88a2bfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff89d14e0a066711a6c54140748f7178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2011ce99f8101db484390d4f638a356c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-12 |
| filingDate | 2021-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_224bfb80082fb550394cd088ea08d08a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edd3ac883a3fb767478ad601a18fd2db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1985835827ac5ce8f69033f3cb62acc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad57759e67e56eca00cbe153a108b08b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46cc9df03d10d35c35864f3b8e30c0dd |
| publicationDate | 2022-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022098768-A1 |
| titleOfInvention | Therapeutic, radiolabeled nanoparticles and methods of use thereof |
| abstract | Provided herein are therapeutic nanoparticles including a radiolabel, a chelator that is covalently linked to the therapeutic nanoparticle and to the radiolabel, and a nucleic acid molecule that is covalently linked to the therapeutic nanoparticle. The therapeutic nanoparticle has a diameter between about 10 nanometers (nm) to about 30 nm, and the therapeutic nanoparticle is magnetic. Also provided are pharmaceutical compositions containing these therapeutic nanoparticles. Also provided herein are methods of decreasing cancer cell invasion or metastasis in a subject having a cancer and methods of treating a metastatic cancer in a lymph node in a subject that require the administration of these therapeutic nanoparticles to a subject. Also provided herein are methods of detecting, diagnosing, and/or monitoring a metastatic cancer tissue in a subject. Also provided herein are methods of preparing these therapeutic nanoparticles. |
| priorityDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 333.