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filingDate 2021-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e8f8bc9fde36c22a1b545aafdb9609c
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publicationDate 2022-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2022098718-A1
titleOfInvention Modified nk cells with reduced ccr5 expression and methods of their use
abstract Modified NK cells with reduced expression of CCR5 are provided. Methods of treating a subject with cancer with the modified NK cells are also provided. In some examples, the modified NK cells also have reduced expression of one or more of CCR1, CXCR6, and CD38, increased expression of one or more of CXCR4, CCR7, and CXCR3, and/or express a chimeric antigen receptor.
priorityDate 2020-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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