| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9e3b6014b56c428f90df9198c169cb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N3-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06N3-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06N20-00 |
| filingDate |
2021-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc790bf04bba908fee1810800d45bed9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e464fd57bf0d5255f223617d8437c766
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c73e88ad528f1009c9cf3c8d15952008 |
| publicationDate |
2022-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022098086-A1 |
| titleOfInvention |
Method for determining sensitivity to parp inhibitor or dna damaging agent using non-functional transcriptome |
| abstract |
The present invention relates to a method for determining sensitivity to a PARP inhibitor or a DNA damaging agent by using a non-functional transcriptome, and more particularly, to a method for determining sensitivity to a PARP inhibitor or a DNA damaging agent by extracting nucleic acids from a biological sample to obtain the expression amount of each of non-functional transcriptomes of DNA repair-related genes, and then analyzing the use rate (TU) of each of the non-functional transcriptomes for each gene on the basis of the obtained expression amount. The method for determining sensitivity to a PARP inhibitor or a DNA damaging agent according to the present invention is useful in that sensitivity can be determined in real time with high accuracy because the method uses information of the transcriptomes transcribed in the gene, unlike existing methods which determine sensitivity to a PARP inhibitor or a DNA damaging agent on the basis of genetic variation information. |
| priorityDate |
2020-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |