http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022097716-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97b37af00ebfa12eb3f070c583f00a0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55d635e782a809567a34cd2f50bc440a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18843 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate | 2021-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0186652c7c903466e26b876cd1fb931f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a347368d0ddc95792022fa7546030597 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c0609a84157fa2ed47951e84e5e2338 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_862e89d1d1c0df6871963f8e8f771e2d |
| publicationDate | 2022-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022097716-A1 |
| titleOfInvention | Method for producing reversibly immortalized cell |
| abstract | The present invention addresses the problem of providing: a method for producing a reversibly immortalized cell, whereby it becomes possible to proliferate a cell having an immortalizing gene introduced therein for a long period without damaging the chromosome in the cell and it also becomes possible to remove the immortalizing gene; and a method for producing a large amount of reversibly immortalized cells which can be cloned and have stabilized quality.　According to the present invention, a method for producing a reversibly immortalized cell is provided, the method comprising: a step for introducing a chromosomally unintegrated RNA virus vector which carries at least one immortalizing gene selected from the group consisting of Bmi-1 gene, TERT gene and SV40T gene into a mammalian cell to express the immortalizing gene in the cell; and a step for culturing the cell to proliferate the cell. |
| priorityDate | 2020-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.