| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_161a8b4565c98a3463575b41dd4c64f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_839626440178fc968fecdd23a653c6b5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-65 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-65 |
| filingDate |
2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f9dd714c1c6961226ae9f8839968e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71c037db589308182cdd1d63b8143851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59d08deab8174b93e6b8a35bf7a518e1 |
| publicationDate |
2022-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022097216-A1 |
| titleOfInvention |
Method for producing recombinant insulin-like growth factor i |
| abstract |
Provided is a method for producing recombinant insulin-like growth factor I (rIGF-1) as an improved method for obtaining correctly folded rIGF-1 with high purity relative to misfolded rIGF-1, the method comprising: (1) a step for obtaining rIGF-1 as a fusion protein (SUMO-IGF-1) of rIGF-1 and a ubiquitin-like protein, small ubiquitin-related modifier (SUMO); (2) a step for treating SUMO-IGF-1 with SUMO protease; and (3) a step for applying the treatment solution in step (2) to cation exchange chromatography to obtain an eluate containing rIGF-1 by means of gradient elution. |
| priorityDate |
2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |