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filingDate 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b395408615f6c4c5fde28db645f65f5e
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publicationDate 2022-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2022094614-A1
titleOfInvention Anti-dpp6 chimeric antigen receptor bearing regulatory t cells
abstract The present disclosure relates generally to regulatory T cells (Tregs) engineered to express a dipeptidyl aminopeptidase-like protein 6 (DPP6)-reactive chimeric antigen receptor (CAR). The engineered Tregs are suitable for use in immunotherapy regimens for autoimmune, inflammatory and degenerative diseases. In particular, the anti-DPP6 CAR expressing Tregs are suitable for treating or preventing autoimmune diseases of the pancreas or central nervous system.
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