| abstract |
Provided in the present invention are a compound of general formula I or a pharmaceutically acceptable salt, a stereoisomer, an ester, a prodrug and a solvate thereof, a preparation method therefor and the use thereof, and in particular, the use of the compound of general formula I or the pharmaceutically acceptable salt, the stereoisomer, the ester, the prodrug and the solvate thereof as an HPK1 kinase inhibitor in the prevention and/or treatment of tumors and diseases caused by or associated with pathogen infection. The above-mentioned compound of general formula I contains at least one deuterium atom, and has high stability and good bioavailability in an animal body. |