Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de793103682ead8e49753520b5df8048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e14356569c586903d67bf959bc1e3f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5a55b337d321ba77a634e42d6b9d59a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0495 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-66 |
filingDate |
2021-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9667505fd0a4b80b01152c3463328c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84dcbdc0fca8a0196df792d26c42204d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3a89161964f74f9dfe23e861bd43265 |
publicationDate |
2022-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022079321-A1 |
titleOfInvention |
Pna probes for pretargeted imaging and therapy |
abstract |
The invention relates to a kit for targeting of a diagnostic or therapeutic agent to a target site comprising: (a) a first conjugate comprising (i) a targeting moiety capable of binding selectively to the target site; and (ii) a first hybridization probe moiety comprising a PNA oligomer; and (b) a second conjugate comprising (i) a second hybridization probe moiety comprising a complementary PNA oligomer; and (ii) a diagnostic agent or a therapeutic agent moiety; wherein the length of the complementary PNA oligomer in the second hybridization probe moiety is not more than 14 bases. The invention further relates to methods for delivering a diagnostic or therapeutic agent to a target site in mammals, as well as methods for the diagnosis or treatment of medical conditions, such as e.g. cancer, in mammals. |
priorityDate |
2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |