abstract |
The present invention relates to a method for purifying paroxetine hydrochloride, the method comprising: (a) adding a solvent and an acid to the paroxetine hydrochloride, and then heating and stirring until the solution is clear; (b) optionally, adding an appropriate amount of activated carbon to the solution, and stirring same for a certain amount of time; (c) filtering, cooling and crystallizing; and (d) after crystallization is complete, separating and drying the product to obtain pure paroxetine hydrochloride. The method for purifying the paroxetine hydrochloride provided in the present invention is easy to operate, and has cheap raw materials and mild conditions, and the obtained pure product of paroxetine hydrochloride does not turn red. |