http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022077276-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ad1a8756578bd91a9dcf292496269a1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-87 |
filingDate | 2020-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a3177d74b654c74a6e69deace10645d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_082be2ff884a28b9df42221b9c5d9ae4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5712bbd574cf8c586b1107653e68ae2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7267794d6e88be5158b2956bab8a930 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7083853febc80ad4476fdbc2dc0f536 |
publicationDate | 2022-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2022077276-A1 |
titleOfInvention | Application of combination of nicotinamide mononucleotide and lactobacillus fermentum in preparation of formulation for relieving skin photoaging |
abstract | Provided is an application of a combination of nicotinamide mononucleotide (NMN) and Lactobacillus fermentum (L. fermentum) in the preparation of a formulation for relieving skin photoaging. Experiments verify that NMN and L. fermentum are combined to activate the AMPK signaling pathway, so as to inhibit the activation of the NF-κB signaling pathway, thus reducing the damage of an inflammatory medium to a mouse. In addition, the activated AMPK can reduce the oxidative damage of skin and improve the overall antioxidant capacity of a body by adjusting levels of associated oxidative stress indicators in the serum, liver, and skin of a mouse. Therefore, the present invention has certain reference significance for the prevention and treatment of UVB induced skin damage, and provides a theoretical basis and available strain sources for the development of NMN and L. fermentum combined formulation. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115960742-A |
priorityDate | 2020-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.