| abstract |
The present invention relates to (poly)peptides comprising a sequence consisting of a LC3-interacting region (LIR) core motif and specific linker peptidic sequences. These (poly)peptides selectively bind, with high affinity, protein(s) of the ATG8 family, and can advantageously be used for the capture and/or the detection of protein(s) of the ATG8 family, as well as the identification of autophagy inhibitors. |