| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef04fb9a5809ffd2a39e03fca9c080c8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-14 |
| filingDate |
2021-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa619e5e2457f490f04c3a34a1f9ef4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9db0e28770d0ec4f692d71bb7315fcb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f193dfe7fcde09191df12f4f9be0a40c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2da96b27e12490eb6d235b48a66c1bd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed38e629874fdd712836b13d552199a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3459c1119bfeb515e76ac028e618b3f0 |
| publicationDate |
2022-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022060987-A1 |
| titleOfInvention |
Triphenyl calcilytic compounds for the treatment of autosomal dominant hypocalcemia type 1 (adh1) |
| abstract |
The present disclosure provides a method of treating an autosomal dominant hypocalcemia type 1 (ADH1) with a therapeutically effective amount of a compound of formula (I), in particular CLTX-305, wherein the therapeutically effective amount of the compound increases a blood calcium concentration (cCa) to a range of about 7.5 mg/dL to about 10.5 mg/dL, such as about 8.5 mg/dL to about 10.5 mg/dL. Also provided herein is a dosing finding method for treating an autosomal dominant hypocalcemia type 1 (ADH1) with a therapeutically effective amount of a compound of formula (I) or CLTX-305 according to one or more dosing regimens. |
| priorityDate |
2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |