Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_007f84474d63a7b3f292ad3861fb30e3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-00 |
filingDate |
2021-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcffe3c5a3c766ca31a20ab6907f0f1f |
publicationDate |
2022-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022056401-A1 |
titleOfInvention |
Methods for identifying compositions for inhibiting viral infectivity |
abstract |
Compositions that inhibit the HIV-1 viral infectivity factor (Vif) and methods of use thereof are provided. The disclosed compositions have inhibitory activity against Vif function and restore A3G enzymatic activity. The disclosed compositions may be used to treat and/or prevent infection and transmission of viruses (such as HIV), to inhibit the function of Vif in a cell, to inhibit viral infectivity in a cell, and to inhibit replication of a virus. Methods of identifying Vif inhibitors are also provided. |
priorityDate |
2020-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |