| abstract |
Provided herein are dissolvable compositions having a porous matrix. The pore-creating excipient in the composition has two parts: quillaja saponins as a blowing agent; and a scaffolding agent selected from cellulose, starches and fibres. Additional excipients, such as pore-size modifying agents, mineral ions, hygroscopicity modifiers and emulsifiers, are added depending on the solubility, hygroscopicity and lipophilicity of the active agent. The porous matrix is suitable for providing dissolvable formulations of prebiotics, bacteriophage, polyphenols, vitamins, plant extracts and other nutritional supplements. Further provided herein are methods of preparing the dissolvable compositions including mixing to a viscosity of 5000-12000 cP and depositing into a stencil or printing the composition into any desirable shape. |