| abstract |
The present invention relates to an injection composition containing isolated mitochondria. More specifically, the present invention relates to a liquid injection composition containing glycine, sugars, a buffer and mitochondria, and a pharmaceutical composition containing the liquid injection composition as an active ingredient. The liquid injection composition according to the present invention strengthens the stability of mitochondria for prevention or treatment of mitochondria-related diseases and prevents and inhibits thrombogenesis in the blood of a subject to whom the composition is administered, and thus can ensure the safety of a mitochondrial therapeutic agent and maintain the activity of mitochondria. Therefore, a composition according to the present invention resolves aggregation, which can occur during the administration of mitochondria into the body, and thus, in order to prevent and treat various diseases caused by mitochondria dysfunction, mitochondria can be safely and effectively injected into the body. |