abstract |
Provided is a chimeric alloantibody receptor (CALAR) specific for alloantibody-based B cell receptor (BCR), wherein the alloantibody is specific for an Rh factor. Also provided are compositions comprising the CALAR, polynucleotides encoding the CALAR, vectors comprising a polynucleotide encoding the CALAR, engineered cells comprising the CALAR, and method using the same. |