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filingDate 2021-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2022048621-A1
titleOfInvention Compositions and methods to target anti-rh antibody
abstract Provided is a chimeric alloantibody receptor (CALAR) specific for alloantibody-based B cell receptor (BCR), wherein the alloantibody is specific for an Rh factor. Also provided are compositions comprising the CALAR, polynucleotides encoding the CALAR, vectors comprising a polynucleotide encoding the CALAR, engineered cells comprising the CALAR, and method using the same.
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