| abstract |
Disclosed are a 1H-pyrazol-4-amide derivative having a structure as represented by formula (I), a preparation method therefor, a pharmaceutical composition containing same, the use thereof as an inhibitor for FGFR and a mutation thereof, the use thereof in the preparation of a drug for treating and/or preventing at least part of FGFR kinase mediated tumors or cancers and a drug for tumor patients having tolerance to FGFR inhibitors, and the use thereof in the preparation of a drug for tumor patients having mutations in V561, V565, N550, N540, V555, E566, K660, and/or V550 of an FGFR signaling pathway. |