| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8ed020d9d1eed3acfa2285b2f55de30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b250a3ec04fef40863fe8bd29ff8802b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14152
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10344
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 |
| filingDate |
2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c95e6be3d556d7e34de1564c5f9c1bd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dca4a9b68ed7919a2723a51e0c9c76b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50e91fa375a92be16fe5444d6bff4c54 |
| publicationDate |
2022-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022038367-A1 |
| titleOfInvention |
Process for making a recombinant aav library |
| abstract |
The present invention relates to a process for producing a library of recombinant adeno-associated virus (AAV) particles which are encapsidated by a variety of different capsid polypeptides. Each recombinant AAV particle in the library comprises an AAV genome which comprises AAV ITRs flanking a first AAV cap gene encoding a first Cap polypeptide, wherein the particles in the library differ in the nucleotide sequences of their first AAV cap genes, and wherein each particle in the library is encapsidated by a Cap polypeptide which is encoded by the cap gene within its AAV genome. The library may be used to screen for recombinant AAV particles which have high specificity for cells of a target therapeutic tissue. |
| priorityDate |
2020-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |