abstract |
The present invention relates to: novel donepezil ether palmitate or a pharmaceutically acceptable salt thereof; and a sustained-release pharmaceutical composition containing same as a main ingredient. Since an ether palmitate group is introduced to donepezil, the donepezil ether palmitate of the present invention reduces the initial release of donepezil, which is the active ingredient, when administered into the body, so as to reduce the risk of side effects such as drug toxicity, and allows donepezil to be uniformly released in the body over a long time to increase drug treatment effects for dementia patients. |