http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022031011-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0272d70c9ba3abebfdf08dc6b96f1120 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2021-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16e6dda3c5598f4759f26e9087f0ccc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfa375f054b56f3a4e5e7f691fe039e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33169d0da6721c601aa3a3e88fe24b83 |
| publicationDate | 2022-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022031011-A1 |
| titleOfInvention | Kinetically acting adjuvant ensemble |
| abstract | The present invention relates to an adjuvant ensemble in which two or more immunostimulatory substances for inducing the activation of various immune cells are combined, and to a novel concept of a kinetically acting adjuvant ensemble and use thereof, in which, when combining immunostimulatory substances having different signaling pathways in an immunostimulatory mechanism, the treatment order and the time interval are adjusted to maximize the finally exhibited synergistic immunostimulatory response. The kinetic action is characterized in that the second immunostimulatory substance responds to intrinsic factors (enzymes, redox potential, GSH, and pH) and extrinsic factors (redox, pH, temperature, photo/light, magnetism, ultrasound, and electrical response) in immune cells, and thus chemical binding at a binding site is cleaved, and the active site is exposed so that function is kinetically recovered, or two or more immunostimulatory substances are sequentially released from a carrier at regular time intervals, thus inducing immune activity. In such a novel immunostimulatory adjuvant ensemble, a first immunostimulatory substance and a second immunostimulatory substance can be selected in a personalized manner according to applications, and the adjuvant ensemble can be used for anticancer effects and the development of drugs for the prevention and treatment of infectious diseases. |
| priorityDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.