http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022023564-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed3c2f63a5b1c705b1b389a6f1f1f7c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b01dcd61775e996fac631d4b10c4e87f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6895 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6895 |
| filingDate | 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10c3bbc20ba03a2fb91f2b1e31066706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba84957af4183b51240cf1c01827563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49e37f078c89015fa42a7190aee682d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b245833426350ea5b39dfb195b2782d |
| publicationDate | 2022-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022023564-A1 |
| titleOfInvention | Whole nucleic acids rt-qpcr method for detecting histoplasma capsulatum fungus pathogen(s), histoplasmosis diagnosis and treatment methods, means thereof |
| abstract | The invention relates to an in vitro method of detecting by RT-qPCR on a sample, presence of a nucleic acid molecule contained in the mitochondrial Small Sub-Unit (mtSSU) gene of Histoplasma capsulatum, or a variant thereof, by Whole Nucleic Acid (WNA) reverse transcriptase qPCR (RT-qPCR). The method can be coupled to an in vitro method of detecting nucleic acid content of Mycobacterium tuberculosis in particular by RT-PCR. The invention also relates to an in vitro method of diagnosing whether an animal or human subject is infected with Histoplasma capsulatum, or has histoplasmosis, optionally whether the animal or human subject has or has a risk to develop tuberculosis, based on the detection method of the invention. The invention can be applied to determining the efficacy of a therapeutic active ingredient. Are also encompassed therapeutic applications for patients diagnosed as having histoplasmosis with the method of the invention, kits and their uses for carrying out a method of the invention, primer nucleic acid molecules. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116179739-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116179739-A |
| priorityDate | 2020-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.