Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3eb16490efe0e156e86dfef95c0fb3c0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be46886b26149204da31b76fd1ed0e89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b59ef2ef19154359a8462405718cd9f |
publicationDate |
2022-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022022669-A1 |
titleOfInvention |
Dual-functional compounds and methods of use |
abstract |
The present disclosure provides a compound configured to release nitric oxide (NO) and inhibit the activity of a phosphodiesterase (PDE) when administered to a subject. The compound may include L 1 and L 2 . L 1 may include a functional group that is part or all of a NO releasing agent. L 2 may include a functional group that is part or all of a PDE inhibitor. The compound may further include a bond or a biradical that connects L 1 and L 2 . The present disclosure further provides a method of treating or preventing a disease using the compound or a composition including the compound. |
priorityDate |
2020-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |