http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022006514-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1174f45dadbe663c57d013f7e55f418 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7ba36909b7d47ea38dbb7662e59543e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e12b6795cd93f8702b6539c1ba843e2 |
publicationDate | 2022-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2022006514-A1 |
titleOfInvention | Immune profiling and methods of using same to predict responsiveness to an immunotherapy and treat cancer |
abstract | The present disclosure provides methods for treating non-small cell lung cancer (NSCLC) in a subject in need thereof by obtaining a biological sample from the NSCLC from the subject; measuring the expression of the genes associated with immune activation in the biological sample; measuring the expression of the genes associated with immune inhibition in the biological sample; determining that the NSCLC is responsive to an immunotherapy where the expression of fifteen or more of the genes associated with immune activation are upregulated and ten or less of the genes associated with immune inhibition are upregulated; and administering an immunotherapy to the subject where the subject is determined to be responsive to the immunotherapy. |
priorityDate | 2020-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.