abstract |
Provided is an anti-CD40 antibody or an antigen-binding fragment. The antibody or the antigen-binding fragment specifically binds to CD40, and can activate antigen-presenting cells, stimulate antigen-presenting cells to release cytokines, induce tumor cell apoptosis, and inhibit tumor cell proliferation. Further provided is the use of the antibody or antigen-binding fragment in the preparation of a drug for treating or ameliorating CD40-related diseases, or the use thereof in the preparation of a kit for diagnosing CD40-related diseases. |