abstract |
Provided in the present invention is a class of tricyclic compounds, a preparation method therefor, and the medical use thereof. The tricyclic compounds are compounds having the structure of the following formula (I) or a pharmaceutically acceptable salt, a prodrug, a tautomer, a stereoisomer, or a mixture of stereoisomers thereof. The compounds of the present invention have a significant activity in terms of antagonizing histamine H 1 receptors, and has fewer side effects against anti-M-choline and a lower hERG toxicity. Specifically, the definitions of each group are as set forth in the description. |