| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-33
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3231 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bf321037ba93d735ccefd9d24a4b902
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df90db992b91a59c7277f769db7e6b1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6db5621b284a64444e87bfec9143e0c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c81d6e5aa9cd7a02f0011e6ecd2ff7c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6e77ab284d2db6b45f786ca0d09c2ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f270ea97dea2f7d103535e36b65e7ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3839b97e26c7f0676d301113fe00c23b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d75453b17f0027e522af06bcbb7e4ad0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdd5b4d9704daf52cda9fe0c20f328c2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_195dbee88ed8410e38ec0374e599954c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05ee566618713d3f5716d5b75c426bea |
| publicationDate |
2021-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021260197-A1 |
| titleOfInvention |
Enhanced oligonucleotides for modulating fubp1 expression |
| abstract |
The present invention relates to enhanced antisense oligonucleotides that are complementary to the Far Upstream Element-Binding Protein 1 (FUBP1) and are capable of reducing a FUBP1 target nucleic acid, such as FUBP1 mRNA. The invention relates to enhanced antisense oligonucleotides targeting FUBP1 or conjugates thereof for use in treating and/or preventing a hepatitis B virus (HBV) infection, in particular a chronic HBV infection. The invention in particular relates to the use of the enhanced antisense oligonucleotides targeting FUBP1 or conjugates thereof for destabilizing cccDNA, such as HBV cccDNA. The invention further relates to enhanced antisense oligonucleotides targeting FUBP1 or conjugates thereof for use in treating cancer. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment and/or prevention of a HBV infection, or its use in the treatment of cancer. |
| priorityDate |
2020-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |