http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021260176-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17206dff5bbf886fd79492d7278c4861 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6018 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
| filingDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3193dc3c4bdf564495d29fd96bff1ca6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3be796d9a46c010d439a9260b0987c62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfd3ff290105a36847b011215c0d3764 |
| publicationDate | 2021-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021260176-A1 |
| titleOfInvention | Synthetic epitopes of betacoronaviruses |
| abstract | The present invention relates to fields of epitope vaccine design. In particular, it relates to a polypeptide comprising an amino acid sequence of SEQ ID NO: 1: X1SNNLDSKVGGNYNYX2YRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQX3YGFQPTNGVGYQPX4, wherein each of X1 to X4 is independently at least one amino acid, or a variant of SEQ ID NO: 1 or a fragment of SEQ ID NO: 1 or a fragment of the variant of SEQ ID NO: 1, and a nucleic acid molecule encoding the polypeptide of the invention. The invention further relates to a conjugate comprising (i) the polypeptide of the invention, (ii) a peptide moiety comprising at least one coiled coil peptide chain segment, and (iii) a lipid moiety. The invention further relates to a synthetic virus-like particle (sVLP) consisting of helical lipopeptide bundles comprising the conjugates of the invention, and its use as a vaccine against SARS-CoV and SARS-CoV-2 diseases and in preventing or treating SARS-CoV and SARS-CoV-2 diseases. |
| priorityDate | 2020-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.