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filingDate 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ff21d5cd456f3771eb399e9d95765e5
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publicationDate 2021-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021259960-A1
titleOfInvention Method and device for extracting and/or amplifying a target nucleic acid
abstract The invention relates to a method for extracting a target nucleic acid (12) from a sample liquid (30). The method comprises the provision of a sample liquid (30) with the target nucleic acid (12) in a reaction vessel (22) and the provision of magnetic microparticles (10) in the sample liquid (30), which are in each case functionalized with at least one extraction nucleic acid (16), wherein the extraction nucleic acids (16) are at least partially complementary to the target nucleic acid (12). The method further comprises a hybridization of at least a part of the target nucleic acid (12) with one of the extraction nucleic acids (16) and binding the target nucleic acid (12) via the extraction nucleic acid (16) to one of the magnetic microparticles (10). Moreover, the method comprises the provision of a magnetic field in the reaction vessel (22) such that at least a part of the magnetic microparticles (10) bound to the target nucleic acid (12) is sedimented on a vessel wall (22a, 22b, 22c) of the reaction vessel (22). Furthermore, devices and methods for amplifying a target nucleic acid (12), the use of magnetic microparticles (10) for extracting a target nucleic acid (12) and a magnetic microparticle are provided.
priorityDate 2020-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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