abstract |
The present invention belongs to the field of virology, in particular to the field of hepatitis B virus treatment. Provided are a model and a method for screening HBV cccDNA inhibitors. According to the screening model and the method, the detection of a split luciferase is used as an alternative index of HBV cccDNA detection, and a cccDNA-targeted drug can be screened in high throughput. |