Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd72346bcce28340209c938e1f72e4be |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate |
2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a90e7c3fc9b9cba64227811a78101f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd471c02d1f837165b3afa23ab3c87dd |
publicationDate |
2021-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021255590-A1 |
titleOfInvention |
An anti-vegf scfv adeno-associated virus (aav) vector and uses thereof |
abstract |
The present invention discloses an adeno-associated virus based viral vector system containing an expression cassette of VEGF neutralizing/ binding antibody scFv packaged in the optimized viral capsids for specific tissue tropism (i.e. different serotypes of AAV). Said vector can be used for the treatment of wet age-related macular degeneration (wet AMD), diabetic retinopathy (DR), diabetic macular oedema (DME), myopic choroidal neovascularization (mCNV), macular oedema following retinal vein occlusion (RVO) and Glioblastoma. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697801-B2 |
priorityDate |
2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |