| abstract |
The present invention generally relates to the field of tissue engineering, particularly tissue engineering in the context of cartilaginous tissues. More specifically, the invention relates to a three-dimensional structure comprising a sufficient number of chondrocytes and a cross-linked biopolymer formulation, wherein said three-dimensional composition has a mechanical stability suitable for implantation into a subject in need thereof. In further aspects, the invention relates to a method for the preparation of such three-dimensional compositions, e.g. via bio-printing, a composition obtainable by such method, and medical uses of the three-dimensional compositions. |