abstract |
A substituted quinazoline compound, and a preparation method therefor, a pharmaceutical composition thereof, and a use thereof. Specifically, the present invention relates to a substituted quinazoline compound having BRK and/or BTK kinase inhibitory activity, a pharmaceutically acceptable salt or pharmaceutically acceptable solvate thereof, a preparation method therefor, a pharmaceutical composition comprising the compound, and the uses of these compounds in the preparation of a medication for preventing or treating a disease associated with a BRK kinase, a BTK kinase, or both in an organism. |