| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe1a3ceb02facedd1911e89546b32231 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20034 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8df5f77fe49d8c8e622fd1edd05feb4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f3c52ac00ddd729ecd7384cdfc80950 |
| publicationDate |
2021-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021254327-A1 |
| titleOfInvention |
Envelope replacement-type viral vector vaccine and construction method therefor |
| abstract |
Disclosed is an envelope replacement-type viral vector vaccine. The Vesicular stomatitis virus VSV is used as a vector, and the GP gene in the VSV virus genome is replaced with a truncated segment of a spike protein S gene of a coronavirus or a fused ECD-CA of an extracellular segment and a GP-C segment of the spike protein S gene of the coronavirus. The truncated segment of the spike protein S gene is selected from genes with some amino acid deletions at the C-terminus, and the ECD-CA is a gene formed by means of fusing the extracellular segment of the spike protein S gene of the coronavirus with the transmembrane and intracellular segment genes of the VSV viral envelope protein. Also disclosed is a method for constructing the envelope replacement-type viral vector vaccine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114540419-A |
| priorityDate |
2020-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |