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filingDate 2021-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1a1a76dabfc4b331ae7aa1dd0ef9219
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publicationDate 2021-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021247188-A1
titleOfInvention Cd73 antagonist potency assay and methods of use thereof
abstract The present disclosure relates to methods of characterizing a CD73 antagonist, which method is suitable as a potency assay. The assay provided herein determines the ability of a CD73 antagonist to inhibit the CD73 -mediated enzymatic conversion of AMP to adenosine. In vitro assays, including those with a CD73 antagonist reference sample, are also provided.
priorityDate 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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