Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2b1ee7d499f6f1e579c7a3bc3059214 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0e4c112c42f7a155a467679cf99e67c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df02dc2eab1779ebc7dfb5accf94318b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-74 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-215 |
filingDate |
2021-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e48bac58ce2dc415f4f0edef82b383f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3deceb2348240fc4c775ed7a01823c4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d12a99e3ab29edb70a6bbaed2869397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c6988958d0968aa6ba7d3b24c983d63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4088277fe6ee7508335778d464cfc5ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_970c2f6c9cbebe13978fed90fa94994d |
publicationDate |
2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021239838-A2 |
titleOfInvention |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes |
abstract |
The Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) pandemic has undeniably emerged as the largest global health threat to humanity in this century. SARS-CoV-2 vaccines will be essential to reduce morbidity and mortality if the virus establishes itself in the population. The inventors have set up candidate vaccines against SARS-CoV-2. In particular, the inventors have identified specific epitopes to be included in vaccine candidates thanks to in silico analysis of the amino-acid sequence of these proteins to map predicted MHC-I and -II epitopes by online software (NetMHC-4.0 and NetMHCII-2.3) and peptide binding prediction software. B cell epitopes were also mapped using online software (BepiPred-2.0 and Discotope), as well as regions rich in epitopes whose sequences are homologous between SARS-CoV-2 and -CoV-1. Finally, the inventors have generated some specific CD40 antibodies comprising one or more SARS-CoV-2 polypeptide(s) of the present invention and that are suitable for vaccine purposes. Therefore, the present invention relates to SARS-CoV-2 polypeptides and uses thereof for vaccine purposes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114807179-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023088968-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2781294-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022043551-A3 |
priorityDate |
2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |