| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9707743a4af90a265188711620a6dc90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4f8755c361b70eb6af66fd6a114e590 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
| filingDate |
2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cc391c1a2b4f6804585eac2480cc42e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1816f6f1762e75898df09f1f489ca7e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58659984711775b80547242c7a343459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd216ff76268042a2b961c8740a2a52f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d980c45b9e9a33bed3139fddad929af9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16390596bf35e6f5c809c8b6698a2b9a |
| publicationDate |
2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021239695-A1 |
| titleOfInvention |
Thiazoloxime and oxazoloxime derivatives as reactivators of organophosphorous nerve agent (opna)-inhibited human acetylcholinesterase for the treatment of nervous and/or respiratory failure after intoxication with opna |
| abstract |
The present invention relates to a compound of formula (I). It also relates to a pharmaceutical composition comprising at least one compound of formula (I) and at least one pharmaceutically acceptable support. Finally, it relates to the compounds of formula (I) for use in a method of medical treatment, preferably in the treatment of a nervous and/ or respiratory failure due to intoxication with at least one organo-phosphorous nerve agent (OPNA); in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer. The compounds act as reactivators of OPNA-inhibited hAChE (human acetylcholinesterase). |
| priorityDate |
2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |