http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021236313-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17f2c91d6073a10f992fe476cb411294 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B35-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B35-10 |
| filingDate | 2021-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c28622250a0fc59825bd5c171b662a9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_315b7091e4fefd30cabd80b7e1fd844c |
| publicationDate | 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021236313-A1 |
| titleOfInvention | Biologics engineering via aptamomimetic discovery |
| abstract | The present disclosure relates to a biologics development platform that derives biologics from aptamers found to bind to a target. Particularly, aspects of the present disclosure are directed to generating sequencing data and analysis data for each unique aptamer of an aptamer library that binds to a target within a monoclonal compartment, inferring aptamer sequences derived from the sequencing data and the analysis data, identifying interaction points between the aptamer sequences and epitopes of the target based on structure or sequence motifs of the aptamer sequences, modeling molecular dynamics of interactions between the aptamer sequences and the epitopes to identify characteristics of the interaction points as requirements or restraints for the interactions, and inferring one or more amino acid sequences based on the characteristics of the interaction points derived from the interactions between aptamer sequences and the epitopes. |
| priorityDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.