http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021222891-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5cc1ba7221a8a65cfecc09c1733126f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2010-0067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B10-0045 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B3-10 |
| filingDate | 2021-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e5e12282e92219e95d0e78a79c58c24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed46bb72cd2e10ad378a3ca2537aa1d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce67995b4a224e893da2587281a5bc76 |
| publicationDate | 2021-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021222891-A1 |
| titleOfInvention | Ocular inserts with analyte capture and release agents |
| abstract | An ocular device for insertion into the eye (for example, into a lacrimal punctum or a conjunctival sac) are described herein. The ocular device may continuously capture specific analytes from tear fluid. Several embodiments of the ocular device may have one or more open channels and pores that enable tears to drain naturally through while capturing specific analytes. A mechanism of detecting analytes in bodily fluids using materials comprised of DNAzymes and/or aptamers are described herein. Aptamers are oligonucleotide or peptide molecules that bind to a specific target molecule. DNAzymes are designed to catalyze a number of biological reactions (i.e., RNA cleavage, DNA cleavage, ligation, or phosphorylation reactions). A number of ways an ocular insert may capture analytes in tear fluid in vivo for subsequent in vitro analysis are described herein. Additionally, a specific mechanism for colorimetric detection of analytes using aptamer- and/or DNAzyme-crosslinked hydrogels are described herein. |
| priorityDate | 2020-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.