http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021207271-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55085ab91a9deb98013194a3e169f831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7004 |
| filingDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_126003fb9c3f49f6a167d822d097e040 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60e28589e477a50e893b18acec67fe39 |
| publicationDate | 2021-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021207271-A1 |
| titleOfInvention | Organoselenide glutathione peroxidase mimetics for the treatment of inflammatory pulmonary disorders |
| abstract | A method is provided for treating an inflammatory pulmonary disorder in a subject by administering to the subject a therapeutically effective amount of an organoselenide glutathione peroxidase mimetic in the context of a prescribed dosage regimen, where the organoselenide has both anti-inflammatory and anti-oxidant activity. The method enables the treatment of pulmonary disorders such as ARDS and pulmonary fibrosis, which may or may not be secondary to a viral or bacterial infection of the lungs. A method is also provided for treating a subject infected with an influenza virus or a coronavirus such as SARS CoV-2 by administration of an antiviral organoselenide glutathione peroxidase mimetic. Formulations comprising an organoselenide glutathione peroxidase mimetic such as ebselen with one or more additional active agents are also provided, as are ebselen formulations for pulmonary administration via oral inhalation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113831302-A |
| priorityDate | 2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.