| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee490adb5ed4d6cbfb79c7ecd754923e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-064 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-196 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-196
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-72 |
| filingDate |
2021-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5df481e5cd87823aa9c962ede17ca223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d922105b333c0b49af462df12f6978e7 |
| publicationDate |
2021-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021203914-A1 |
| titleOfInvention |
Peramivir dry powder inhalant and preparation method therefor |
| abstract |
The present invention relates to a peramivir dry powder inhalant, which is prepared from peramivir or an acceptable salt or a hydrate thereof. A single-dose formulation is 5-30 mg, the particle size D10 of dry powder is 1.3-2.2 um, D50 is 3-6 um, and D90 is 6-13 um. The peramivir dry powder inhalant can effectively reduce the titer of influenza A viruses in the lungs of a mouse, has a significant anti-virus effect, can significantly prolong survival time and reduces the death rate, and the pharmacodynamic effect of the peramivir dry powder inhalant is superior to those of a peramivir sodium chloride injection and oseltamivir phosphate. The peramivir dry powder inhalant has a specific lung targeting effect, and the effectiveness and safety of the medicine are significantly improved. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023187393-A1 |
| priorityDate |
2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |