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filingDate 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021202449-A1
titleOfInvention Nanoparticle-loaded silicified cells, methods of making, and methods of use
abstract A silicified cell includes a nanoparticle that carries a bioactive agent. The silicified call can be a tumor cell, a bacterial cell, a virus, or a silicifiable compartment or fragment thereof. The silicified cell can optionally include an immunomodulatory moiety that may be carried within pores of the nanoparticle and/or bound to the surface of the nanoparticle. The silicified call can be used as a prophylactic or therapeutic treatment for treating tumors or bacterial infections.
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