| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e86a9b2d42401a91a10241a80521f67f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6891 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 |
| filingDate |
2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18eff76f8cdf3f09d218fd041958ea81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad273e09a14250626bae5a029484b767
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2108318b1bec112c8d8e619c300f5c41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c27db3d752db6ff4686bcb919f6d41d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d83f6a5ba63fff6d58af081eb8e7c8 |
| publicationDate |
2021-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021195598-A2 |
| titleOfInvention |
Degrader-antibody conjugates and methods of using same |
| abstract |
Degrader-antibody conjugates (DACs) are described, comprising anti-TM4SF1 antibodies, and antigen-binding fragments thereof. Degrader molecules as described comprise a ubiquitin E3 ligase binding group (E3LB) and a protein binding group (PB). Linkers may be utilized between the antibodies and the degrader molecules (L1) and between the ubiquitin E3 ligase binding group (E3LB) and the protein binding group (PB) of the degrader molecule (L2). Methods of use of said DACs are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535607-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023056069-A1 |
| priorityDate |
2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |