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filingDate 2021-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5e8b2be61ae8ded1d6105724f485001
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publicationDate 2021-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021191485-A1
titleOfInvention Biomarkers for predicting a patient's response to bcg therapy, methods and uses based thereon
abstract The present invention relates to an in vitro method for predicting the response of a bladder cancer patient to Bacillus Calmette-Guérin (BCG) immunotherapy, which comprises determining the expression level or ratio of expression levels of miRNAs or combinations of miRNAs in a sample and comparing said expression level, or ratio of expression levels, to a reference value, wherein a difference in said comparison is indicative of said patient's response to BCG therapy. The present invention also relates to kits for carrying out such methods and to uses of miRNAs, or combinations of miRNAs, to predict whether or not a bladder cancer patient will respond to BCG therapy.
priorityDate 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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