| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65a4bfbc6c5520b3746e4e245c65a350 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate |
2021-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf4ba23ff6271282176f9f83e6054e73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f58f778d1ab4ae27fc1c962677b9b375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4b60e243ddf354eb36d180ba4f84b21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b85d22aa0397e424ca47a8da72ffe85 |
| publicationDate |
2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021155825-A1 |
| titleOfInvention |
Use of pax6 gene or expression product thereof in preparation of drug for inhibiting fibrosis |
| abstract |
Provided is the use of a PAX6 gene or an expression product thereof in the preparation of a drug for inhibiting fibrosis. Experiments confirm that PAX6 can inhibit fibrosis promotion factor TGFβ and promote fibrosis inhibitory factors IL1R2 and CXCL10, so that the effects of protecting the heart and inhibiting fibrosis can be achieved, and therefore, in terms of the heart, PAX6 is a potential brand-new important target for treating heart fibrosis so as to prevent heart failure. |
| priorityDate |
2020-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |