| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B8-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-39 |
| filingDate |
2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a12d97672c82fc49a67905568a30ad24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f69c21b915d524d5ef07b9f6fad1c3d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_710df0179e9628f4d0dad7ebe3a403c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21481bf7dfc27935a1e372f92da5260d |
| publicationDate |
2022-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021155025-A8 |
| titleOfInvention |
Method of preventing or treating pancreatic dysfunction or diabetes by upregulating human cathelicidin ll-37 to inhibit islet amyloid polypeptide (iapp) self-assembly |
| abstract |
A method for treating type 2 diabetes (T2D) is provided. The method comprises diagnosing a subject as suffering from T2D or as being pre-diabetic; monitoring the response to glucose stimulation of at least one islet in the pancreas of the subject by quantitatively imaging glucose metabolism in vivo ; establishing a target range for the response to glucose stimulation of the at least one islet; and upregulating cathelicidin gene expression in the subject until the monitored response to glucose stimulation is within the target range. |
| priorityDate |
2020-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |