| abstract |
Provided is an improved method for producing a pancreatic islet-containing capsule. This method for producing a pancreatic islet-containing capsule includes: (a) a step for preparing a sodium alginate solution A containing pancreatic islands at a concentration of at least 10,000 IEQ/mL; (b) a step for dropping the sodium alginate solution into a divalent cation solution and collecting gelled particles; (c) a step for adding the particles collected in the step (b) to a poly-L-ornithine solution A, stirring the mixture, and then collecting particles; (d) a step for adding the particles collected in the step (c) to a sodium alginate solution B, stirring the mixture, and then collecting particles; and (e) a step for adding the particles collected in the step (d) to a sodium citrate solution, stirring the mixture, and then collecting particles. |