| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_680dd0699e3f4ba8532d128c7152b3bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2021-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2daf92791df57894f8dd96d09171543e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a07684ca7569525865fc9f569d9e417
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e80be30367cb75083681b9ca5772290 |
| publicationDate |
2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021151081-A1 |
| titleOfInvention |
Photostable fluorescent proteins |
| abstract |
Provided herein are photostable fluorescent proteins and methods of making and using those proteins. A photostable fluorescent protein variant is provided comprising an amino acid sequence that is at least 90% identical to SEQ ID NO:3, wherein the amino acid sequence comprises a first substitution at a residue corresponding to residue 46 of a polypeptide of SEQ ID NO:2 and a second substitution at a residue corresponding to residue 63 of the polypeptide of SEQ ID NO:2, and the variant is more photostable than the polypeptide of SEQ ID NO:2. A method of detecting a protein of interest is also provided, comprising the steps of expressing a fusion protein and detecting the fluorescence of the fusion protein, thereby detecting the protein of interest. |
| priorityDate |
2020-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |