| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60e66be87630d7cef0ce770e1d898eec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2525-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0629 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2021-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ab0ea2c92943fc9b6caa6784c42b675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f6d7dc65f36e37b51d42231f18833ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_209e59f83439924452aaf670f9026ad3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84bea2aa2e37d6516d91bcadadd9c45b |
| publicationDate |
2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021149761-A1 |
| titleOfInvention |
Three-dimensional culture of immortalized skin cells having superficial layer formed from stratum corneum, method for producing said three-dimensional culture, and method for evaluating test substance using said three-dimensional culture |
| abstract |
Provided is a three-dimensional culture (10) of immortalized skin cells, the culture being characterized by being a layered culture comprising a plate-shaped substrate (1) and immortalized skin cells (2) adhered to the surface of the plate-shaped substrate, and a superficial layer (3) thereof being constituted by a stratum corneum layer. The three-dimensional culture can be produced by inoculating an upper surface of a culture-broth-impregnable plate-shaped substrate with immortalized skin cells, and three-dimensionally culturing under stress on the superficial layer of an immortalized skin cell layer formed by the layering of the immortalized skin cells. The sensitizing properties of a test substance can be evaluated using this three-dimensional culture. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022066937-A1 |
| priorityDate |
2020-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |